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Neglected tropical diseases, or NTDs, are a group of preventable and treatable illnesses that affect the world’s most vulnerable populations. While not always fatal, their effects can be devastating. NTDs cause chronic pain, blindness, and disfigurement, contributing to a cycle of poverty that keeps children out of school and adults out of work.

The human toll is steep — but we are fighting back. Together.

Every January, organizations like Â鶹¹ú²ú observe World NTD Day to raise awareness of the suffering these diseases create for more than 1 billion people worldwide. The day offers an opportunity to reflect on decades of progress in reducing hardships caused by NTDs while fortifying future actions toward eradication and elimination.

Since its founding, Â鶹¹ú²ú has remained committed to battling NTDs. Today we combat five World Health Organization-designated diseases: Guinea worm, river blindness, trachoma, schistosomiasis, and lymphatic filariasis. Working alongside countries and communities, a broad spectrum of partners, and with the support of many donors, we prioritize affordable, community-focused methods for treatment and prevention. This approach has helped millions of people live healthier, more productive lives.

Across Africa, Asia, and Latin America, we have assisted 22 countries in the elimination of at least one disease. With the Center’s support, more than 1 billion doses of generously donated essential medicines have been delivered to communities in need.

One achievement, however, highlights what’s possible when we work together to tackle daunting challenges.

In 1986, Â鶹¹ú²ú made the bold decision to lead an international campaign to eliminate Guinea worm disease. Since then, annual cases have declined from an estimated 3.5 million to just a handful worldwide. For the first time, a world free of Guinea worm disease is within reach.

But the work is far from over — and we have no intention of stopping now.

Together, we’ll confront neglected tropical diseases. Together, we’ll end them.

To learn more about our work on NTDs and the people whose lives have been transformed, explore the stories below: